产品描述
| 熔点 | 285°C(lit.) |
| 溶解性 | H2O: 0.5 mg/mL，methanol: 6 mg/mL，dilute aqueous acid: insoluble. |
| 存贮条件 | 储存温度-20°C |
| 应用 |
Prazosin hydrochloride has been used: · to block the α1adrenergic receptors that mediate sympathetic vasoconstriction in mice. · as an α1-adrenoceptor blocker,administered intragastrically in rats. · as a vasodilator,administered together with inuslin into the left ventricle of mice for the assessment of its effects on renal functions. |
| 产品介绍 | Prazosin hydrochloride (盐酸哌唑嗪)是α肾上腺素阻断剂，可作用于高血压、焦虑和恐慌症等 |
| 生化机理 | Peripheral α1-adrenoceptor antagonist; vasodilator. Prazosin can be used to treat chronic posttraumatic stress disorder (PTSD). It plays a role in reducing blood pressure by relaxing blood vessels, hence used in the treatment of high blood pressure. |
| 别名 | 盐酸哌唑嗪;脉哌斯;脲宁平;1-(4-氨基-6,7-二甲氧基-2-喹唑啉基)-4-(2-呋喃甲酰)哌嗪盐酸盐;1-(4-氨基-6,7-二甲氧基-2-喹唑啉基)-4-(2-呋喃甲酰基)哌嗪盐酸盐；脉宁平盐酸盐;1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine Hydrochloride |
