产品描述
| 产品介绍 | Carprofen 抑制犬科COX2，IC50为30 nM。 |
| 生化机理 | Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that has been found to have antimicrobial activity. Carprofen is primarily used as a veterinary analgesic and anti-inflammatory for arthritis and pain. Its anti-inflammatory activity is due to cyclooxygenase inihbition with selectivity for COX-2 inhibition, while its antimicrobial activity is less certain. Carprofen can kill B. subtilis by permeabilizing its membrane. Other studies have shown carprofen can target the Escherichia coli DNA polymerase III β subunit. |
| 别名 | 卡洛芬; 6-氯-α-甲基-9H-咔唑-2-乙酸;Carprofen; 6-Chloro-α-methyl-9H-carbazole-2-acetic Acid |
