产品描述
| 沸点 | 93-94°C |
| 折光率 | 1.396-1.4 |
| 敏感性 | 对热和湿度敏感 |
| 溶解性 | Soluble in chloroform, ethanol (50% w/w), esters, ketones, and hydrocarbons.Slowly soluble in water with hydrolytic decomposition yielding ethanol and CO2., Soluble in chloroform, ethanol (50% w/w), esters, ketones, and hydrocarbons.Slowly soluble in wate |
| 存贮条件 | 储存温度 2-8°C; 充氩保存 |
| 密度 | 1.1010 |
| 应用 | 蛋白质组氨酸和酪氨酸的修饰试剂。也是RNA酶的化学修饰剂,它和RNA酶的活性基团组氨酸的咪唑环反应而抑制RNA酶活性。 |
| 产品介绍 | Diethyl Pyrocarbonate has been shown to inhibit ryanodine binding to ryanodine/Ca2+ receptor channels in skeletal muscle in a dose- and time-dependent manner and increases the Ca2+ permeability of SR vesicles. This compound could be useful for specific inactivation of nucleases during isolation of undegraded polynucleotides. Diethyl Pyrocarbonate also inhibits PAF Acetylhydrolase (platelet-activating factor acetyl hydrolase), and has been used as a probe for the topography of 5.8S rRNA in yeast ribosomes. |
| 生化机理 | 在溶液中浓度约为 0.1% (v/v) 时可使 RNase 失活，从而防止 RNA 被降解。 |
| 别名 | 氧二甲酸二乙酯;DEPC;DEP;氧二甲酸二乙酯;焦炭酸二乙酯;重碳酸二乙酯;DEP; DEPC; Diethyl dicarbonate; Diethyl oxydiformate; Ethoxyformic acid anhydride; Pyrocarbonic acid diethyl ester; |
