敏感性 | 对光线敏感 |
溶解性 | 不溶于水,微溶于乙醇、甲醇,溶于苯、甲苯、二甲苯、氯仿、乙醚、丙酮等。 |
存贮条件 | 阴凉干燥通风处存储。 |
密度 | 1.0000 |
应用 | A polycyclic aromatic hydrocarbon (PAH), environmental pollutant and carcinogen. Used as a chemical carcinogen in experimental models of cancer. Carcinogenesis depends on it′s oxidation by CYP1A1 to benzo[a]pyrenediolepoxide, that forms depurinating adducts with DNA that dissociate to form abasic lesions. Benzo[a]pyrene is a ligand for the arylhydrocarbon receptor (AhR), and some of its biological effects, including the induction of CYP1A1, appear to be mediated via activation of the AhR. |
别名 | 3,4-苯并芘3,4-Benzpyrene Benzo[def]chrysene Benzo[a]pyrene |