熔点 | 267°C(lit.) |
存贮条件 | 储存温度2-8℃ |
应用 | A camptothecin derivative that inhibits DNA topoisomerase I. |
生化机理 | 10-Hydroxycamptothecin is a camptothecin derivative that inhibits DNA topoisomerase by enacting strand breaks in chromosomal DNA and inducing apoptosis.10-Hydroxycamptothecin is an inhibitor of Topo I. |
别名 | 10-羟基喜树碱;10-Hydroxycamptothecin; (4S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3’,4’:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; Hydroxycamptothecin; |