熔点 | 229-234°C |
折光率 | 1.5455-1.5475 |
溶解性 | Soluble in DMSO, 100% ethanol, and methanol |
存贮条件 | 储存温度2-8℃ |
密度 | 1.3800 |
应用 | An apoptosis inducer and precursor to paclitaxel/taxol |
产品介绍 | Baccatin III is the precursor to paclitaxel/ taxol. Antileukaemic and antitumor agent isolated from the bark of the Pacific yew tree (Taxus breviofolia). Baccatin III binds to tubules when they are assembled in the cell and stabilizes the polymerized form of tubules so that they remain assembled even under conditions in which microtubules dissociate into tubulin subunits. Baccatin III is also an inducer of apoptosis and shows antitumor properties in vitro |
别名 | 巴卡丁三O-De[(2R,3S)-3-(Benzoylamino)-2-hydroxy-3-phenylpropanoyl]paclitaxel |