敏感性 | 对热敏感 |
溶解性 | Soluble in Chloroform and Methanol |
应用 | An angular furocoumarin, may be used as a photoactivatable molecule that reacts with DNA and unsaturated fatty acids to form monoadducts. Angelicin may be studied as a potential phototherapeutic and to understand its mechanisms of action and effects on RNA and DNA synthesis. |
生化机理 | Angular furocoumarin with diverse photobiological effects. Upon long-wavelength UV irradiation, forms monoadduct with double-stranded DNA and reacts with unsaturated fatty acids. Inhibits DNA and RNA synthesis and cell replication in Ehrlich ascites tumor cells. |
别名 | 异补骨脂素;2H-氟[2,3-h]色满-2-酮;氟[2,3-h]苯并吡喃-2-酮Furo[2,3-h]benzopyran-2-one;2H-Furo[2,3-h]chromen-2-one;Isopsoralen;2-Oxo-(2H)-furo(2,3-h)-1-benzopyran |