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Erythropoietin/EPO Protein, Human (CHO)

MCE 国际站：Erythropoietin/EPO Protein, Human (CHO)

Erythropoietin/EPO Protein, Human (CHO)可保护心肌不受缺血——再灌注损伤，促进有益的重构。

Synonyms: rHuEPO; Epoetin; EPO

Species: Human

Source: CHO

Biological Activity: The ED₅₀ is <1 ng/mL as measured in a cell proliferation assay using TF-1 human erythroleukemic cells, corresponding to a specific activity of >1.0 × 10⁶ units/mg.

研究背景：Erythropoietin (EPO), originally identified for its critical hormonal role in promoting erythrocyte survival and differentiation, is a member of the large and diverse cytokine superfamily. EPO and EPOR function as the primary mediators of a general protective response to tissue hypoxia, which acts to maintain adequate tissue oxygenation through adjustments of circulating red cell mass by using a hormonal feedback-control system involving the kidney and the bone marrow. EPO and EPORs are also expressed by other tissues and organs, including the brain and heart. EPO has also been shown to stimulate mitosis and signaling in astrocytes, endothelial cells, cardiomyoblasts, and cardiomyocytes maintained in vitro.

蛋白编号：P01588 (A28-R193)

基因 ID：2056

产品分类：细胞因子和生长因子

Categories：Cytokines and Growth Factors

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