MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

Gypenoside L

CAS No. : 94987-09-4

MCE 国际站：Gypenoside L

产品活性：Gypenoside L 是一种皂苷，存在于 Gynostemma pentaphyllum 中。Gypenoside L 增加 SA-β-半乳糖苷酶活性，促进衰老相关分泌细胞因子的产生。Gypenoside L 还可以激活 p38 和 ERK MAPK 通路和 NF-κB 通路以诱导衰老。Gypenoside L 具有抗肿瘤和抗炎活性。

研究领域：MAPK/ERK Pathway  |  Stem Cell/Wnt  |  NF-κB

作用靶点：p38 MAPK  |  ERK  |  NF-κB

结构分类：萜类  |  三萜

来源：植物  |  葫芦科  |  绞股蓝

In Vitro: Gypenoside L (20-80 μg/mL; 24 h) increases the mRNA expression levels of SASP, such as IL-1α, IL-6, TIMP-1, CXCL-1 and CXCL-2 in HepG2 and ECA-109 cells.
Gypenoside L (20-80 μg/mL; 24 h) causes cell cycle arrest at S phase.
GPL (3.125-100 μg/mL) significantly inhibits LPS-induced NO accumulation in RAW264.7 cells.

相关产品：Natural Product Library Plus  |  Bioactive Compound Library Plus  |  Immunology/Inflammation Compound Library  |  Kinase Inhibitor Library  |  MAPK Compound Library  |  NF-κB Signaling Compound Library  |  Stem Cell Signaling Compound Library  |  Natural Product Library  |  Anti-Cancer Compound Library  |  Anti-Aging Compound Library  |  Antioxidant Compound Library  |  Glycoside Compound Library  |  Oxygen Sensing Compound Library  |  Terpenoids Library  |  Pyroptosis Compound Library  |  Glutamine Metabolism Compound Library  |  Traditional Chinese Medicine Active Compound Library  |  Neuroprotective Compound Library  |  Anti-Lung Cancer Compound Library  |  Anti-Pancreatic Cancer Compound Library  |  Anti-Cancer Metabolism Compound Library  |  Neurodegenerative Disease-related Compound Library  |  Angiogenesis-Related Compound Library  |  Transcription Factor-Targeted Library  |  Anti-Cancer Natural Product Library  |  Antidepressant Compound Library  |  Anti-inflammatory Traditional Chinese Medicine Active Compound Library  |  Plant-Sourced Natural Product Library  |  Osteogenesis Compound Library  |  Heterocyclic Compound Library  |  Pain-Related Compound Library  |  Membrane Protein-targeted Compound Library  |  Bisabolangelone  |  IMD-ferulic  |  Karacoline  |  5-Hydroxy tryptophol β-D-glucuronide-d₄  |  LM22B-10  |  Mangiferin  |  4-Hydroxylonchocarpin  |  Insulin Detemir  |  Dauricine  |  (rac)-AG-205  |  Poricoic acid A  |  Ginsenoside Rg1  |  GS143  |  QNZ  |  5-Aminosalicylic Acid-d₃ hydrochloride  |  Lucyoside B  |  Sulindac  |  Colistin adjuvant-1  |  Penehyclidine  |  Tauroursodeoxycholate  |  Pyrrolidinedithiocarbamate ammonium  |  Vanillic acid  |  Dehydroevodiamine hydrochloride  |  Isovitexin  |  Corynoxeine  |  TLR4/NF-κB/MAPK-IN-1  |  Gossypin  |  Broussonin E  |  L-threo-Sphingosine  |  ERK1/2 inhibitor 1

热门产品线：重组蛋白  |  化合物库  |  天然产物  |  荧光染料  |  PROTAC  |  同位素标记物  |  寡核苷酸  |  抗体  |  点击化学

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent Dye  |  PROTAC  |  Isotope-Labeled Compounds  |  Oligonucleotides  |  Antibodies  |  Click Chemistry

货号: HY-N8211

品牌介绍:
•   MCE (MedChemExpress) 拥有200 多种全球独家化合物库，我们致力于为全球科研客户提供前沿最全的高品质小分子活性化合物；
•   50,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领；
•   产品种类涵盖各种重组蛋白，多肽，常用试剂盒 ，更有 PROTAC、ADC 等特色产品，广泛应用于新药研发、生命科学等科研项目；
•   提供虚拟筛选，离子通道筛选，代谢组学分析检测分析，药物筛选等专业技术服务；
•   设有专业的实验中心和严格的质控、验证体系；
•   提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；
•   产品的生物活性多经各国客户实验验证；
•   Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；
•   专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；
•   与世界各大制药公司及知名科研机构建立了长期的合作。