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CAS No. : 50700-72-6
MCE 国际站:Vecuronium bromide
产品活性:Vecuronium (ORG NC 45) bromide 是一种非去极化神经肌肉阻滞剂,也可作为烟碱乙酰胆碱受体 (nAChR) 抑制剂,肌肉松弛剂,可用于手术前麻醉。
研究领域:Membrane Transporter/Ion Channel | Neuronal Signaling
作用靶点:nAChR
In Vitro: Vecuronium bromide (0-100 μM, 15 min) inhibits [3H] norepinephrine (NE) uptake to 65% at 100 μM in adrenal medullary cells.Vecuronium bromide (0-15 μM,72 hours) inhibits cancer cell proliferation and migration in a concentration-dependent manner.Vecuronium bromide (0-15 μM,72 hours) can significantly reduce cell viability by combining with cisplatin.
In Vivo: Vecuronium bromide (Intravenous injection, 0-5 μM, every 30 min, 2 hours) attenuates the response of carotid sinus nerve activity (CSNA) to hypoxia in a dose-dependent manner and inhibits the neural response of the carotid body to acetylcholine (ACh) in Wister rats.
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货号: HY-B0118A
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