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CAS No. : 802918-57-6
MCE 国际站:Silybin
产品活性:Silybin 是一种从草蓟 (Silybum marianum) 种子中分离出来的黄素寡糖。Silybin 诱导凋亡 (apoptosis),并具有保肝,抗氧化,抗炎,抗癌活性。
研究领域:Apoptosis
作用靶点:Apoptosis
In Vitro: Silybin (0-200 mM; for 72 hours) has growth inhibition in a time- and dose-dependent manner.
Silybin (68 μM; for 72 hours) induces apoptosis and increases the cells in G1-phase of ~22%.
Silybin (68 μM; for 72 hours) induces AKT activity inhibition.
In Vivo: Silybin (50, 100 mg/kg/day; given intragastrically for the last 4 weeks) significantly lowers both serum and hepatic lipid accumulation.
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