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SIEVE software compares LC/MSn spectra from healthy and disease (or control versus treatment) samples to find differentially expressed features. Trend analysis can be preformed to detect changes associated with dosage effects or time points, enabling comparison of multiple classes of samples. Thanks to the pre-filtering of the SIEVE software, only peptides or metabolites that show statistically significant differences in abundance between sample sets or over time need be identified through the incorporated search capabilities.
Key Features and Benefits