等温滴定量热仪美国TA仪器DSC/DTA 应用于蛋白
价格:面议

等温滴定量热仪美国TA仪器DSC/DTA 应用于蛋白

产品属性

  • 品牌TA仪器
  • 产地
  • 型号NANO ITC
  • 关注度233
  • 信息完整度
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产品描述

美国TA仪器DSC/DTANANO ITC可以用在蛋白行业领域,用来检测蛋白质,可完成表征结合项目。符合多项行业标准表征结合。

Proteomics research is uncovering a vast array of new proteins, including enzymes. It is now clear that the old assumption that one gene encodes one protein in incorrect. One gene can encode for several proteins, and many proteins have multiple functions: which function is displayed is controlled by the protein’s molecular environment. The structure and function of a protein are controlled by interactions with macromolecules such as other proteins, nucleic acids and lipids. Studying a protein in isolation (for example, obtaining the crystal or NMR structure of a purified protein) is critical to establishing a structural basis for the protein’s function(s). However, true functional characterization of the protein generally requires manipulation of multi-component systems under stringently-controlled conditions, and evaluating the roles of the physical characteristics of the protein. Proteomics has highlighted the need for a technique that can quantify the interactions between molecules under physiologically-relevant conditions.

    Nano ITC能够检测到1纳摩尔或更少量的生物样品,所产生低至100纳焦耳的微小热量变化。所采用的固态热电加热及冷却系统能够精确地控制温度,并用独特的抽取式注射器来精确有效地传送样品。Nano ITC的等温功率补偿设计,能在zei快的反应时间内进行及时地补偿。


     技术参数

Nano ITC1.JPG


     ITC 技术

    生命科学研究学者认为,大分子间交互作用的热力学驱动力是设计高效的生物医学和药物治疗的重要关键。因而,量热技术迅速成为表征大分子稳定性和分子间交互作用驱动力的首选方法。量热法分析是基于准确地测量生物分子与另一大分子、配体(结合研究)或基体(动力学研究),专一性或非专一性交互作用的吸热或放热速率。TA仪器的Nano ITC(标准体积及小体积)是强而有力的生物热分析工具,能够精准且有效地进行这些重要测量。

    Nano ITC是专为纳摩尔级生物分子的高灵敏度分析而设计,能改善实验室产出与工作效率。这是藉由结合高灵敏度量热计、准确且稳定的温度控制系统及高效率的样品传送注射器来达成。


     仪器介绍:

TA仪器

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