热烈恭喜世界各地的化学研究者使用Syrris流动化学系统，并在世界知名杂志上发表了50多篇文章。

 随着科学技术的不断发展，推动着更加先进仪器的问世，继而为科技的发展如虎添翼。流动化学的兴起是近几年来化学领域最大的一次变革，随着流动化学的高效、安全、清洁等优势逐渐被研究者认可，越来越多的研究者开始选择用流动化学来做反应。 以下是2006年-2013年Syrris流动化学系统助力研究者们发表的文章，且呈逐年增多的趋势。2013Continuous Flow Synthesis of n‑Alkyl Chlorides in a High-Temperature Microreactor EnvironmentBenedikt Reichart, Guenter Tekautz, and C. Oliver Kappe*Org. Process Res. Dev., 2013, 17 (1), 152–157.Continuous-Flow Microfluidic Electrochemical Synthesis: Investigating a New Tool for Oxidative ChemistryGregory P. Roth*, Romain Stalder, Toby R. Long, Daryl R. Sauer and Stevan W. DjuricJ. Flow Chem., 2013, In Press.Hydrogen-Free Alkene Reduction in Continuous FlowAndrew S. Kleinke, Timothy F. JamisonOrg. Lett., 2013, 15 (3), 710–713.Microreactor-Mediated Organocatalysis: Towards the Development of Sustainable Domino ReactionsLaura Carroccia, Biagia Musio, Leonardo Degennaro, Giuseppe Romanazzi and Renzo Luisi*J. Flow Chem., 2013, In Press.A comprehensive study on the activity and deactivation of immobilised Lecitase Ultra in esterifications of food waste streams to monoacylglycerolsKaren M. Gonçalves, Felipe K. Sutili, Ivaldo I. Júnior, Marcella C. Flores, Leandro Soter de Mariz e Miranda, Ivana C.R. Leal, Yraima Cordeiro, Rafael Luque* and Rodrigo Octavio M. Alves de Souza*ChemSusChem., 2013, 6 (5), 872-9.Continuous-Flow Synthesis of Adipic Acid from Cyclohexene Using Hydrogen Peroxide in High-Temperature Explosive RegimesDr. Markus Damm, Bernhard Gutmann, Prof. Dr. C. Oliver KappeChemSusChem, 2013, In Press.Biocatalyzed Acetins Production Under Continuous-Flow Conditions: Valorization of Glycerol Derived From Biodiesel IndustryIngrid C. R. Costa, Ivaldo Itabaiana Jr., Marcella C. Flores, Ana Clara Lourenço, Selma G. F. Leite, Leandro S. de M. e Miranda, Ivana C. R. Leal and Rodrigo O. M. A. de Souza*J. Flow Chem., 2013, In Press.Nickel nanocrystals: fast synthesis of cubes, pyramids and tetrapodsMeital Shviro and David Zitoun*RSC Advances, 2013, 3, 1380.Biocatalytic preparation of dichloropropyl acrylates. Application to the synthesis of poly(dichloropropyl acrylates)Yara-Varón Edinson, Eras Joli Jordi, Torres Mercè, Balcells Mercèa, Villorbina Gemma, Canela-Garayoa RamonJournal of Molecular Catalysis B: Enzymatic, 92, (2013), 7– 13.Continuous Flow Valorization of Fatty Acid Waste Using Silica-Immobilized LipasesIvaldo Itabaiana Jr, Felipe K. Sutili, Selma G. F. Leite, Karen M. Goncalves, Yraima Cordeiro, Ivana C. R. Leal, Leandro S. M. Miranda, Manuel Ojeda, Rafael Luque, Rodrigo O. M. A. de SouzaGreen Chem., 2013, 15, 518-524.Greening heterogeneous catalysis for fine chemicalsValerica Pandarus, Rosaria Ciriminna, François Béland, Genevieve Gingras, Maxime Drobot,Omar Jina, Mario PagliaroTetrahedron Letters, 54 (2013) 1129–1132.Kinetic resolution of 5H-pyrrolo[1,2-a]imidazol-7-ol, 6,7-dihydro under continuous flow conditions: An intermediate for chiral ionic liquids synthesisAmanda S. De Miranda, Juliana C. Gomes, Manoel T. Rodrigues Jr., Ingrid C.R. Costa, Wanda P. Almeida, Raquel de O. Lopes, Leandro S.M. Miranda, Fernando Coelho, Rodrigo O.M.A. de SouzaJournal of Molecular Catalysis B: Enzymatic 91 (2013) 77– 80.Ethyl acetate as an acyl donor in the continuous flow kinetic resolution of (±)-1-phenylethylamine catalyzed by lipasesAmanda S. de Miranda, Leandro S. M. Miranda and Rodrigo O. M. A. de Souza*Org. Biomol. Chem., 2013, 11, 3332.Kinetic resolution of a precursor for myo-inositol phosphates under continuous flow conditionsEvelin A. Manoel, Karla C. Pais, Marcella C. Flores, Leandro Soter de M. e Miranda, Maria Alice Zarur Coelho, Alessandro B.C. Simas, Denise M.G. Freire, Rodrigo Octavio M.A. de SouzaJournal of Molecular Catalysis B: Enzymatic 87 (2013) 139–143.Micro-continuous flow synthesis of gold nanoparticles and integrated deposition on suspended sheets of graphene oxideMarek Wojnicki, Magdalena Luty-Błocho, Justyna Grzonka, Krzysztof Pacławski, Krzysztof J. Kurzydłowski, Krzysztof FitznerChemical Engineering Journal, 225, (2013), 597–606.Lipase-catalyzed esterification of steric hindered fructose derivative by continuous flow and batch conditionsFelipe K. Sutili, Halliny S. Ruela, Selma G.F. Leite, Leandro S. de M. Miranda, Ivana C.R. Leal, Rodrigo O.M.A. de SouzaJournal of Molecular Catalysis B: Enzymatic 85– 86 (2013) 37– 42.Lipase-catalyzed synthesis of secondary glucose esters under continuous flow conditionsHalliny S. Ruela, Felipe K. Sutili, Ivana C. R. Leal, Nakedia M. F. Carvalho, Leandro S. M. Miranda and Rodrigo O. M. A. de SouzaEur. J. Lipid Sci. Technol. 2013, 115, 464–467.The synthesis of platinum nanoparticles and their deposition on the active carbon fibers in one microreactor cycleMagdalena Luty-Błocho, Marek Wojnicki, Krzysztof Pacławski, Krzysztof FitznerChemical Engineering Journal, 226, (2013), 46–51.2012Continuous stream processing: a prototype magnetic field induced flow mixerPeter Koos, Duncan L. Browne and Steven V. Ley *Green Process Synth 1 (2012): 11–18.Silver nanowires and nanoparticles from a millifluidic reactor: application to metal assisted silicon etchingRonen Gottesman, Alex Tangy, Ilan Oussadon and David Zitoun*New J. Chem., 2012, 36, 2456–2459.Synthesis of poly(ethyl acrylate-co-allyl acrylates) from acrylate mixtures prepared by a continuous solvent-free enzymatic processEdinson Yara-Varo´n, Jordi Eras Joli, Merce Balcells, Merce Torres and Ramon Canela-Garayoa*RSC Advances, 2012, 2, 9230–9236.TEMPO-Mediated Electro-oxidation of Primary and Secondary Alcohols in a Microfluidic Electrolytic CellJoseph T. Hill-Cousins, Jekaterina Kuleshova, Robert A. Green, Peter R. Birkin, Derek Pletcher, Toby J. Underwood, Stuart G. Leach and Richard C. D. Brown*ChemSusChem, 2012, 5, 326–331.Liquid-Liquid Two-phase Flow Patterns in a Serpentine MicrochannelP. S. Sarkar, K.K. Singh, K. T. Shenoy, A. Sinha, Hanmanth Rao, and Sandip Kumar GhoshInd. Eng. Chem. Res., 2012, 51 (13), 5056-5066.The methoxylation of N-formylpyrrolidine in a microfluidic electrolysis cell for routine synthesisJekaterina Kuleshova, Joseph T. Hill-Cousins, Peter R. Birkin, Richard C.D. Brown, Derek Pletcher, Toby J. UnderwoodElectrochimica Acta, 69, (2012), 197–202.Copper(I)-Catalyzed Azide–Alkyne Cycloadditions in Microflow: Catalyst Activity, High-Temperature Operation, and an Integrated Continuous Copper Scavenging UnitAlvaro Carlos Varas, Timothy Noel, Qi Wang, and Volker Hessel*ChemSusChem, 2012, Vol. 5, Issue 9, 1703-1707.2011An Automated Process for a Sequential Heterocycle Multicomponent Reaction: Multistep Continuous Flow Synthesis of 5-(Thiazol-2-yl)-3,4-Dihydropyrimidin-2(111)-onesNicholas Pagano, Ananda Herath and Nicholas D. P. Cosford*J. Flow. Chem., 2011, I, 28-31.Effectiveness of mouse minute virus inactivation by high temperature short timetreatment technology: A statistical assessmentMarie Murphy, Guillermo Miro Quesada, Dayue Chen*Biologicals, 39, (2011), 438-443.Safe and Reliable Synthesis of Diazoketones and Quinoxalines in a Continuous Flow ReactorLaetitia J. Martin,* Andreas L. Marzinzik, Steven V. Ley, and Ian R. BaxendaleOrganic Letters, 2011, Vol. 13, No. 2, 320-323.Continuous-flow reactor–based synthesis of carbohydrate and dihydrolipoic acid–capped quantum dotsPaola Laurino, Raghavendra Kikkeri and Peter H Seeberger*Nature Protocols, Vol. 6, No. 8, 2011, 1209-1220.Continuous-flow enantioselective α-aminoxylation of aldehydes catalyzed by a polystyrene-immobilized hydroxyprolineXacobe C. Cambeiro, Rafael Martín-Rapún, Pedro O. Miranda, Sonia Sayalero, Esther Alza, Patricia Llanes and Miquel A. Pericàs*Beilstein J. Org. Chem. 2011, 7, 1486–1493.Enhanced catalysis under flow conditions using SiliaBond functionalized silica gelsValerica Pandarus, Genevieve Gingras, Francois Beland, Rosaria Ciriminna and Mario PagliaroCatal. Sci. Technol., 2011, 1, 1600-1604.The Microwave-to-Flow Paradigm: Translating High-Temperature Batch Microwave Chemistry to Scalable Continuous-Flow ProcessesDr. Toma N. Glasnov*, Prof. Dr. C. Oliver Kappe*Chemistry - A European Journal, 2011, Volume 17, Issue 43, pages 11956–11968.2010Fully Automated Continuous Flow Synthesis of Highly Functionalized Imidazo[1,2-a] HeterocyclesAnanda Herath, Russell Dahl, and Nicholas D. P. Cosford*Organic Letters 2010 Vol. 12, No. 3 412-415.Automated Generation and Reactions of 3-Hydroxymethylindoles inContinuous-Flow MicroreactorsThomas Tricotet and Donal F. O_Shea*Chem. Eur. J. 2010, 16, 6678 – 6686One-Step Continuous Flow Synthesis of Highly Substituted Pyrrole-3-carboxylic Acid Derivatives via in Situ Hydrolysis of tert-Butyl EstersAnanda Herath and Nicholas D. P. Cosford*Organic Letters, 2010, 12 (22), 5182-5185.Continuous flow processing from microreactors to mesoscale: theBohlmann–Rahtz cyclodehydration reactionMark C. Bagley,* Vincenzo Fusillo, Robert L. Jenkins, M. Caterina Lubinu and Christopher MasonOrg. Biomol. Chem., 2010, , 2245–2251Little Artifices of Huge Libraries: Secrets of Parallel Liquid-Phase SynthesisE. V. BabaevRussian Journal of General Chemistry, 2010, Vol. 80, No. 12 pp. 2607–2616.Microreactor Technology as an Efficient Tool for Multicomponent ReactionsAna Cukalovic, Jean-Christophe M.R. Monbaliu, and Christian V. StevensTop Heterocycl Chem (2010) 23: 161–198.2009A Convenient and Stable Synthon for Ethyl Azide and Its Evaluation in a[3 + 2]-Cycloaddition Reaction under Continuous-Flow ConditionsRob Tinder, Roger Farr,† Richard Heid, Ralph Zhao, Randy S. Rarig, Jr.,and Thomas Storz*,Organic Process Research & Development 2009, 13, 1401–1406.Gold Nanoparticles Synthesis in a Flow Microreactor Stabilized with a PVA (polyvinyl alcohol)M. Wojnicki K. Pacławski, M. Luty-Błocho, K. Fitzner, P. Oakley, A. StrettonRudy Metale, 12, (2009), 848-851.Facile, Fast and Safe Process Development of Nitration and Bromination Reactions Using Continuous Flow ReactorsJacques Pelleter* and Fabrice RenaudOrganic Process Research & Development, 2009, 13, 698–705.Conditions of the microdroplets formation in microreactorsM. Wojnicki K. Pacławski, M. Luty-Błocho, K. Fitzner, P. Oakley, A. StrettonRudy Metale, 9, (2009), 528-541.2008Rapid Multistep Synthesis of 1,2,4-Oxadiazoles in a Single Continuous Microreactor SequenceDaniel Grant, Russell Dahl, and Nicholas D. P. Cosford*J. Org. Chem., 2008, 73 (18), 7219-7223.Evaluation of Microfluidics Reactor Technology on the Kinetics of Virus InactivationMark R. Bailey, Dayue Chen, Warren R. Emery, Peter K. Lambooy, Juliana Nolting, Michelle T. Quertinmont, and Parviz A. ShamlouBiotechnology and Bioengineering, 2008, Vol. 99, Issue 6, 1384-1391.Determination of log D via Automated Microfluidic Liquid-Liquid ExtractionMuhammad Alimuddin, Daniel Grant, Daryl Bulloch, Noelle Lee, Martin Peacock, and Russell DahlJ. Med. Chem., 2008, 51 (16), 5140-5142.Continuous Biodiesel Production with Continuous Liquid-Liquid Extraction and Online MS AnalysisElizabeth Crawford, Russell Dahl, Douglas Duquette,1 Daniel Grant,4 Richard Gray, Brian Musselman, Martin Peacock, James PetersenFuel Chemistry Division Preprints 2008Fluorination reactions in microreactorsTomas Gustafsson, Ryan Gilmour and Peter H. Seeberger*Chem. Commun., 2008, 3022–3024.2007[3 + 2] Cycloaddition of acetylenes with azides to give 1,4-disubstituted1,2,3-triazoles in a modular flow reactorChristopher D. Smith, Ian R. Baxendale, Steve Lanners, John J. Hayward, Stephen C. Smith andSteven V. Ley*Org. Biomol. Chem., 2007, , 1559–1561. Tagged phosphine reagents to assist reaction work-up by phase-switched scavenging using a modular flow reactorChristopher D. Smith, Ian R. Baxendale, Geoffrey K. Tranmer, Marcus Baumann, Stephen C. Smith,Russell A. Lewthwaite and Steven V. Ley*Org. Biomol. Chem., 2007, , 1562–1568.Mesoscale Flow Chemistry: A Plug-Flow Approach to Reaction OptimisationRob C. Wheeler,* Otman Benali, Martyn Deal, Elizabeth Farrant, Simon J. F. MacDonald, and Brian H. WarringtonOrganic Process Research & Development, 2007, 11, 704710.2006A flow process for the multi-step synthesis of the alkaloid natural product oxomaritidine: a new paradigm for molecular assemblyIan R. Baxendale, Jon Deeley, Charlotte M. Griffiths-Jones, Steven V. Ley,* Steen Saaby andGeoffrey K. TranmerChem. Commun., 2006, 2566–2568.A flow reactor process for the synthesis of peptides utilizing immobilized reagents, scavengers and catch and release protocolsIan R. Baxendale, Steven V. Ley,* Christopher D. Smith and Geoffrey K. TranmerChem. Commun., 2006, 4835–4837.

领域：原料药/中间体,化学药