AffiSelectTubulinLoadingControlAntibody-分析测试百科网

产品描述

Description

Microtubules are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape. Tubulin itself is a globular protein consisting of two poly- peptides (alpha and beta tubulin). Alpha and beta tubulin dimers are assembled to 13 protofilaments that form a microtubule of 22-nm diameter. Tyrosine ligase adds a C-terminal tyrosine to monomeric alpha tubulin. Assembled microtubules can again be detyrosinated by a cytoskeleton- associated carboxy-peptidase. Detyrosinated alpha tubulin is referred to as Glu-tubulin. Another post-translational modification of detyrosinated alpha tubulin is C-terminal polyglutamylation, which is characteristic of microtubules in neuronal cells and the mitotic spindle. This antibody makes an excellent loading control.

Cat No	Size	Price($)

A0050-001	100ug	198

Application

ELISA: 1:5,000 - 1:25,000

WB: 1:500 - 1:3,000

IF: 1:500 - 1:2,000

OTHER: User Optimized

Specification

Human, Mouse, Rat , Chicken, Hamster, Cow, Dog, Pig, Rabbit

Concentration

1.08 mg/m, Liquid, 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01% (w/v) Sodium Azide