| Catalogue Number | ANT-238 | |||
| Synonyms | IRAP, IL1F3, IL1RA, IL-1ra3, ICIL-1RA, IL1RN, IL1 inhibitor, IL-1ra, MGC10430. | |||
| Type | Mouse Anti Human Monoclonal. | |||
| Introduction | Interleukin-1 ra is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. | |||
| Clone | NYR-hIL1RA. | |||
| Immunogen | r.Human IL-1RA. | |||
| Ig Subclass | Mouse IgG2b. | |||
| Purification Method | Ion exchange. | |||
| Protein concentration | 1mg/ml in PBS (after reconstitution). | |||
| Shipping Conditions | Antibody is shipped lyophilized at ambient temperature. | |||
| Storage Procedures | In lyophilized form, for long periods, store at 4oC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20oC. | |||
| Reconstitution | Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf LifeTwo years lyophilized, one month in solution at 4oC. | |||
| Applications | Direct ELISA, Western Blot, Immuneprecipitation. | |||
| Titer | By direct ELISA, 1:10,000 dilution will yield 0.8 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories). | |||
| Usage | Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. | |||
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