| Catalogue Number | ANT-273 | ||
| Type | Hamster Anti Mouse Monoclonal. | ||
| Introduction | CD28 co-stimulation is necessary for CD4 positive T-cell proliferation & survival, interleukin-2 production, and T-helper type-2 development. Human post-thymic regulatory T cells require CD28 co-stimulation to expand and maintain potent suppressive function in vivo. Apoptosis plays a key role in the age-related decline of CD28 expression and in immunosenescence. | ||
| Clone | NYRmCD28. | ||
| Immunogen | Purified mouse purified mouse LN T cells. | ||
| Ig Subclass | Hamster IgG. | ||
| Purification Method | Protein-A. | ||
| Protein concentration | 1mg/ml in PBS (after reconstitution). | ||
| Storage Procedures | Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. | ||
| Reconstitution | Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf LifeTwo years lyophilized, one month in solution at 4°C. | ||
| Antibody Properties | Blocking and staining antibody. For staining, use 10µl/106 cells. Titer for blocking T cell activation should be determined by the investigator. | ||
| Available Conjugates | This antibody is only available non-conjugated to Biotin. | ||
| Usage | ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. | ||
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