| Catalogue Number | ANT-252 | ||||
| Synonyms | Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein. | ||||
| Type | Mouse Anti Human Monoclonal. | ||||
| Introduction | CD14 (also known lipopolysaccharide (LPS) receptor) is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation. CD14 has been shown to bind apoptotic cells. | ||||
| Clone | hCD4. | ||||
| Immunogen | Purified human B Cells. | ||||
| Ig Subclass | Mouse IgG1. | ||||
| Purification Method | Ion exchange column. | ||||
| Protein concentration | 1mg/ml in PBS (after reconstitution). | ||||
| Storage Procedures | Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. | ||||
| Reconstitution | Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf LifeTwo years lyophilized, one month in solution at 4°C. | ||||
| Antibody Properties | For staining, use 10 µl/106 cells. | ||||
| Available Conjugates | This antibody is also available as purified antibody and conjugated to FITC. | ||||
| Usage | ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. | ||||
| Related Products |
|
