ACK antibody
Cat.#: S0926
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: Q07912
Mol Weight: 119.37kDa
Size: 100ug
Description
This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq]
Recommended Applications
WB
Applications and Recommended Dilution Factors
WB: 1:500-1:3000
Species Reactivity
Human
Other species have not been tested
Products Data
Sample(30ug of whole cell lysate)
A:Raji
7.5% SDS PAGE
diluted at 1:500
Specificity
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 88 and 346 of Human TNK2
Storage Condition and Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.
Alternative Names
TNK2 antibody, ACK antibody, ACK1 antibody, FLJ44758 antibody, FLJ45547 antibody, p21cdc42Hs antibody, Activated CDC42 kinase 1 antibody, Tyrosine kinase non-receptor protein 2 antibody
