| Catalogue Number | ANT-199 | ||
| Synonyms | MGC26137, MOG, MYELIN-OLIGODENDROCYTE GLYCOPROTEIN. | ||
| Type | Mouse Antibody Monoclonal. | ||
| Introduction | MOG is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. MOG is involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified Minor component of the myelin sheath is involved in completion and/or maintenance of the myelin sheath and in cell- cell communication. | ||
| Clone | NYRMOG. | ||
| Immunogen | synthetic pMOG 35-55. | ||
| Ig Subclass | mouse IgG1. | ||
| Purification Method | Ion exchange column. | ||
| Protein concentration | 1mg/ml in PBS (after reconstitution). | ||
| Shipping Conditions | Antibody is shipped lyophilized at ambient temperature. | ||
| Storage Procedures | In lyophilized form, for long periods, store at 4oC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20oC. | ||
| Reconstitution | Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf LifeTwo years lyophilized, one month in solution at 4oC. | ||
| Titer | By direct ELISA, 1:10,000 dilution will yield 0.5 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories). | ||
| Applications | Direct ELISA, Western Blot, Immuneprecipitation, immunohistochemistry. | ||
| Usage | Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. | ||
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