| Catalogue Number | ANT-197 | ||||
| Synonyms | GH1, GH, GHN, GH-N, hGH-N, Pituitary growth hormone, Growth hormone 1, Somatotropin. | ||||
| Type | Mouse Anti Human Monoclonal. | ||||
| Introduction | GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. | ||||
| Clone | NYRhGH. | ||||
| Immunogen | r.Human Growth Hormone. | ||||
| Ig Subclass | Mouse IgG1. | ||||
| Purification Method | Ion exchange. | ||||
| Protein concentration | 1mg/ml in PBS (after reconstitution). | ||||
| Shipping Conditions | Antibody is shipped lyophilized at ambient temperature. | ||||
| Storage Procedures | In lyophilized form, for long periods, store at 4oC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20oC. | ||||
| Reconstitution | Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf LifeTwo years lyophilized, one month in solution at 4oC. | ||||
| Applications | Direct ELISA, Western Blot, Immuneprecipitation. | ||||
| Titer | By direct ELISA, 1:10,000 dilution will yield 0.5 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories). | ||||
| Usage | Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. | ||||
| Related Products |
|
