ADA antibody
Cat.#: 3298-1
Rabbit Monoclonal Antibody
Clone ID: EPR4438
Swiss Prot: P00813
Mol Weight: 41kDa
Size: 100ul
Description
ADA is an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this protein and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia (1).
Recommended Applications
WB, ICC, IP
Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000
ICC: 1:250 - 500
IP: 1:10 - 100
Species Reactivity
Human, Rat
Species cross-reactivity is based on WB analysis
Products Data
Western blot analysis on (A) Jurkat, (B) fetal thymus, and (C) rat kidney lysates using anti-ADA RabMAb (cat. #3298-1).
Specificity
A synthetic peptide corresponding to residues in human ADA was used as an immunogen.
Storage Condition and Buffer
Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Alternative Names
ADA antibody, - antibody, Adenosine deaminase antibody, Adenosine aminohydrolase antibody
Description References
1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1; 33: D54-8.
