| 货号 | CAS号 | 价格 |
|---|---|---|
| B101897-100g | 2632-13-5 | ￥1,759.00 |
| B101897-25g | 2632-13-5 | ￥639.00 |
| B101897-5g | 2632-13-5 | ￥199.00 |
| 熔点 | 69-71°C |
| 溶解性 | Soluble in DMSO, water (partly miscible), most organic solvents, and methanol. |
| 存贮条件 | 储存温度2-8℃ |
| 密度 | 1.4480 |
| 应用 | A cell-permeable, covalent and potent protein tyrosine phosphatase inhibitor. |
| 产品介绍 | PTP inhibitor II is a cell-permeable, covalent and potent PTP (protein tyrosine phosphatase) inhibitor. The compound acts by binding the catalytic domain of the SH2 domain-containing phosphatase SHP-1(DSH2). PTP inhibitor II binds with lower affinity than PTP Inhibitor I (Ki = 128 μM and Ki = 43 μM respectively). The inhibition can be reversed by irradiation of the inactivated PTP at 350 nm. PTP inhibitors have demonstrated enhanced clonogenic survival, mutagenesis and cell growth. PTP inhibitors can also be useful for probing signal transduction pathways as well as drugs for treatment of PTP-related diseases. PTP Inhibitor II is an inhibitor of PTP1B and SH-PTP1. |
| 别名 | 4-甲氧基-α－溴代苯乙酮; ω-溴-4-甲氧基苯乙酮;4-甲氧基苯甲酰基甲基溴;对甲氧基-α-溴代苯乙酮;α-溴-4-甲氧基苯乙酮;4'-甲氧基苯甲酰甲基溴;alpha-溴-4-甲氧基苯乙酮;4-Methoxyphenacyl bromide;ω-Bromo-4-methoxyacetophenone;4-(Bromoacetyl)anisole;α-Bromo-4'-methoxyacetophenone;4'-Methoxyphenacyl Bromide;alpha-Bromo-4-methoxyacetophenone;Bromomethyl 4-methoxyphenyl ketone; 2-Bromo-1-(4-methoxyphenyl)ethanone |
