| 货号 | CAS号 |
|---|---|
| J125527-10mg | 443797-96-4 |
| J125527-5mg | 443797-96-4 |
| J125527-2mg | 443797-96-4 |
| J125527-50mg | 443797-96-4 |
| 溶解性 |
|
| 存贮条件 | 储存温度-20°C |
| 备注 | JNJ-7706621 is pan-CDK inhibitor with the highest potency on CDK1/2 with IC50 of 9 nM/4 nM and showing >6-fold selectivity for CDK1/2 than CDK3/4/6. It also potently inhibits Aurora A/B and has no activity on Plk1 and Wee1. |
| 生化机理 |
JNJ-7706621 is a dual cyclin-dependent kinases and aurora kinases inhibitor with IC50 of 9 and 11 nM for CDK1/Cyclin B and aurora-A, respectively. |
