货号 | CAS号 |
---|---|
D127802-50mg | 74588-78-6 |
D127802-10mg | 74588-78-6 |
溶解性 | DMSO 100 mM Ethanol 20 mM |
存贮条件 | 储存温度-20°C |
生化机理 |
D-64131 is a novel inhibitor of Tubulin polymerization that competitively binds with [(3)H]colchicine to αβ-Tubulin. D-64131 is cytotoxic and inhibits tumor cell proliferation in vitro (IC50 = 74 nM). D-64131 prevents growth of tumor models in mice following oral administration in vivo. D-64131 has significant potential in cancer treatment. |
别名 | ; |