MK-1775

属性

溶解性	DMSO 80 mg/mL Water 0.0001 mg/mL Ethanol <1 mg/mL
存贮条件	储存温度-20°C

描述

备注	MK-1775 is a potent and selective Wee1 inhibitor with IC50 of 5.2 nM; hinders G2 DNA damage checkpoint. Phase 2.
生化机理	MK-1775 is a potent and selective Wee1 kinase inhibitor with an IC50 of 5.2 nM.
别名	2-allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-(4-(4-methylpiperazin-1-yl)phenylamino)-1,2-dihydropyrazolo[3,4-d]pyrimidin-3-one;2-allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-(4-(4-methylpiperazin-1-yl)phenylamino)-1,2-dihydropyrazolo[3,4-d]pyrimidin-3-one