AN-2690

属性

溶解性	10 mM in DMSO
存贮条件	储存温度-20°C

描述

产品介绍	AN-2690(Tavaborole)是抗真菌剂，对发癣菌属有抑制性，对甲癣有潜在应用可能。
生化机理	AN-2690, a broad-spectrum drug, is a very promising candidate for treatment of ungual and periungual infections with improved nail penetration and low keratin binding. AN-2690 is an antifungal agent with activity against Trichophyton species. AN-2690 inhibits yeast cytoplasmic leucyl-tRNA synthetase by formation of a stable tRNA(Leu)-AN2690 adduct in the editing site of the enzyme. AN-2690 is currently in clinical trials for onychomycosis topical treatment.
别名	5-氟-1,3-二氢-1-羟基-2,1-苯并氧杂硼戊环;AN2690;AN 2690;Tavaborole;AN2690;AN 2690;1,3-Dihydro-5-fluoro-1-hydroxy-2,1-benzoxaborole; 5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole;5-fluoro-1,3-dihydro-2,1-benzoxaborol-1-ol;