| 应用 |
A selective telomerase inhibitor. |
| 产品介绍 |
BIBR 1532是一种有效的，选择性的，非竞争性的端粒酶抑制剂，IC50为100 nM。 |
| 备注 |
BIBR 1532 is a potent, selective, non-competitive telomerase inhibitor with IC50 of 100 nM. |
| 生化机理 |
BIBR 1532 is a compound suggested to act as a selective and specific TERT (telomerase) inhibitor. Studies indicate that BIBR 1532 inhibits the TERT (reverse transcriptase of telomerase, hTERT), and shortens the length of the telomere. In addition, reports indicate that BIBR 1532 has the ability to stop cell proliferation in lung cancer cell studies after 120 days. |
| 别名 |
BIBR1532;BIBR-1532; 2-[[(2E)-3-(2-萘基)-1-氧代-2-丁烯基]氨基]苯甲酸;BIBR1532; BIBR-1532;2-[[(2E)-3-(2-Naphthalenyl)-1-oxo-2-butenyl]amino]benzoic acid;(E)-2-(3-(naphthalen-2-yl)but-2-enamido)benzoic acid |
