| 应用 |
A selective fatty acid amide hydrolase (FAAH) inhibitor. |
| 产品介绍 |
PF-3845是一种有效的，选择性的，不可逆的FAAH抑制剂，Ki为230 nM，对FAAH2几乎没有作用活性。 |
| 合法信息 |
Sold for only research purposes |
| 备注 |
PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2. |
| 生化机理 |
PF 3845 is a potent, selective, and irreversible FAAH (fatty acid amide hydrolase) inhibitor. Suggested to function by by carbamylating FAAH’s serine nucleophile. |
| 别名 |
PF 3845; N-3-吡啶基-4-[[3-[[5-(三氟甲基)-2-吡啶基]氧基]苯基]甲基]-1-哌啶甲酰胺;PF 3845; PF3845;N-3-Pyridinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methyl]-1-piperidinecarboxamide |
