Dapivirine (TMC120)

属性

溶解性	DMSO 34 mg/mL Water <1 mg/mL Ethanol <1 mg/mL
存贮条件	储存温度-20°C

描述

产品介绍	Dapivirine (TMC120)是一种非核苷类抑制剂，作用于HIV逆转录酶，IC50为24 nM，抑制多种不同类型的HIV-1分离株，包括多种耐NNRTI的分离株。
备注	Dapivirine is a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM, inhibits a broad panel of HIV-1 isolates from different classes, inclucing a wide range of NNRTI-resistant isolates. Phase 3.
别名	R 147681; TMC 120; TMC 120; R147681;;R 147681; TMC 120; TMC 120; R147681;4-[[4-[(2,4,6-Trimethylphenyl)amino]-2-pyrimidinyl]amino]benzonitrile