| 应用 |
A H4 histamine receptor antagonist. |
| 产品介绍 |
JNJ-7777120是第一个，有效的，选择性非咪唑histamine H4 receptor拮抗剂，Ki为4.5 nM，比作用于其他组胺受体选择性高1000倍以上。 |
| 备注 |
JNJ-7777120 is the first potent and selective non-imidazole histamine H4 receptor antagonist with Ki of 4.5 nM, exhibits >1000-fold selectivity over the other histamin receptors. |
| 生化机理 |
JNJ7777120 is a potent, selective non-imidazole H4 histamine receptor antagonist. |
| 别名 |
(5-氯-1H-吲哚-2-基)(4-甲基哌嗪-1-基)甲酮;JNJ7777120;JNJ7777120;1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methyl-piperazine;(5-Chloro-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone |
