货号 | CAS号 |
---|---|
E129595-1g | 57-63-6 |
E129595-25g | 57-63-6 |
E129595-5g | 57-63-6 |
熔点 | 181.0 - 185.0℃ |
旋光率 | -28.0 to -32.0 deg(C=0.4, Pyridene) |
敏感性 | 对光线敏感 |
溶解性 | Soluble in ethanol (59 mg/ml at 25 °C), DMF (~20 mg/ml), DMSO (59 mg/ml at 25 °C), water (0.01 mg/ml at 27 °C), and methanol. |
应用 | A synthetic estradiol analog. |
生化机理 | Ethynyl Estradiol is a synthetic analog of estradiol, often used in combination with a progestin. Efficacy of administration is facilitated by the ethynyl substitution at the C-17 position, which inhibits first pass hepatic metabolism. Rapidly absorbed from gastrointestinal tract. |
别名 | 炔雌醇;17α-炔雌醇;乙炔雌二醇;17α-乙炔基雌二醇;17α-乙炔-1,3,5-(10)-雌甾三烯-1,17-二醇;3-羟基-19-去甲-17α-甾-1,3,5(10)-三烯-20-炔-17-醇;17α-乙炔基-1,3,5(10)-雌甾三烯-1,17β-二醇;19-去甲-1,3,5(10),17α-雌甾三烯-20-炔-3,17-二醇;17α-Ethynylestradiol;17α-Ethynyl-1,3,5(10)-estratriene-3,17β-diol;19-Nor-1,3,5(10),17α-pregnatrien-20-yne-3,17-diol |