| 应用 |
An MCR antagonist. |
| 产品介绍 |
Eplerenone是醛固酮拮抗剂，IC50为0.36 μM。 |
| 备注 |
Eplerenone is an aldosterone antagonist with an IC50 of 0.36 μM. |
| 生化机理 |
Eplerenone is an aldosterone antagonist with more specificity for the mineralocorticoid receptor (MCR) than spironolactone, having lower affinity for progesterone, androgen, and glucocorticoid receptors. |
| 别名 |
依普利酮;9,11α-乙氧基-17-羟基-3-氧-17α-孕-4-烯-7α,21-二羧酸-γ-内甲酯;Inspra; Epoxymexrenone;9,11α-Epoxy-17-hydroxy-3-oxo-17α-pregn-4-ene-7α,21-dicarboxylic Acid γ-Lactone Methyl Ester;Pregn-4-ene-7,21-dicarboxylic acid 9,11-epoxy-17-hydroxy-3-oxo gamma-lactone methyl ester |
