| 货号 | CAS号 |
|---|---|
| E126576-10mg | 143664-11-3 |
| E126576-50mg | 143664-11-3 |
| E126576-100mg | 143664-11-3 |
| 溶解性 | Soluble in chloroform, dichloromethane, DMSO, and methanol. |
| 存贮条件 | 储存温度-20°C |
| 应用 | A prototypical BCRP (ABCG2) inhibitor. |
| 产品介绍 | Elacridar(GF120918; GW0918)是P-糖蛋白抑制剂，在体内外实验中常作为工具化合物。 |
| 生化机理 | A prototypical BCRP (ABCG2) and MDR-1 inhibitor which inhibits the Bcrp1-mediated transport. It increases the availablity of cytotoxic antitumor drugs. Allows the uptake of more anti-HIV drugs in the brain and CNS. |
| 别名 | GF120918;GW0918;GG918;GF-120918;GF 120918;依克立达; N-[4-[2-(6,7-二甲氧基-3,4-二氢-1H-异喹啉-2-基)乙基]苯基]-5-甲氧基-9-氧代-10H-吖啶-4-甲酰胺;GF120918;GW0918;GG918;GF-120918;GF 120918;N-[4-[2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-9,10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide |
