Entacapone

属性

溶解性	Soluble in DMSO (61 mg/ml at 25 °C), methanol, DMF (~30 mg/ml), and ethanol (~5 mg/ml). Insoluble in water
存贮条件	储存温度 2-8°C

描述

应用	A peripherally acting inhibitor of catechol-O-methyl transferase.
产品介绍	Entacapone抑制儿茶酚-O-甲基转移酶(COMT)活性,IC50,151 nM.
生化机理	(E)-Isomer of Entacapone polymorphic form A. Peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian.
别名	恩他卡朋; (E)-2-氰基-3-(3,4二羟基-5-硝基苯)-N,N二乙基丙烯酰胺;2-Cyano-N,N-diethyl-3-(3,4-dihydroxy-5-nitrophenyl)propenamide