| 应用 |
A phosphodiester, cGMP, and non-specific nucleoside transport inhibitor. |
| 产品介绍 |
Dipyridamole是一种磷酸二酯酶抑制剂，通过红细胞和血管内皮细胞，抑制腺苷的摄取和代谢。 |
| 备注 |
Dipyridamole (Persantine) is a phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. |
| 生化机理 |
Dipyridamole is a PDE (phosphodiesterase) inhibitor with antioxidant properties. This compound has been shown to suppress high glucose-induced osteopontin mRNA expression and protein secretion, as well as inhibit cAMP and cGMP hydrolysis. Research indicates that Dipyridamole is a non-specific nucleoside transport inhibitor with the ability to increase the effects of adenosine in sinoatrial and atrioventricular nodes. Dipyridamole is an inhibitor of ENT1 and ENT2 |
| 别名 |
双嘧达莫;潘生丁; 双嘧哌胺醇; 2,6-双(二羟乙基氨基)-4,8-二哌啶基嘧啶并[5,4-d]嘧啶;2,6-Bis(diethanolamine)-4,8-dipiperidinopyrimido[5,4-d]pyrimidine;2,2',2'',2'''-[(4,8-Dipiperidinylpyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetrakisethanol;Persantin; Curanty |
