| 应用 |
A prodrug for tazarotenic acid with selective affinity for RARβ and RARγ. |
| 产品介绍 |
Tazarotene是外用维甲酸，是一种处方药，制成霜或凝胶出售。 |
| 备注 |
Tazarotene is a prescription topical retinoid sold as a cream or gel. |
| 生化机理 |
Tazarotene is an acetylenic retinoid prodrug of tazarotenic acid with selective affinity for retinoic acid receptors RARβ and RARγ. Tazarotene also upregulates tazarotene-induced genes (TIGs), including the cell adhesion molecule TIG1 and the tumor-suppressor TIG3. |
| 别名 |
他扎罗汀; 6-[2-(4,4-二甲基二氢苯并噻喃-6-基)乙炔基]吡啶-3-甲酸乙酯;6-[(3,4-Dihydro-4,4-dimethyl-2H-1-benzothiopyran-6-yl)ethynyl]-3-pyridinecarboxylic acid ethyl ester ;AGN-190168 ;ethyl 6-[2-(4,4-dimethylthiochroman-6-yl)ethynyl] nicotinate;Tazorac; Zorac |
