Rebamipide

属性

溶解性	Soluble in DMSO (74 mg/mL at 25 °C), methanol (Heat), water (<1 mg/mL at 25 °C), and ethanol (<1 mg/mL at 25 °C).

描述

应用	An inducer of endogenous prostaglandin and a oxygen-derived free radical scavenger.
产品介绍	Rebamipide 是胆囊收缩素-1(CCK1)受体抑制剂，抑制[125I]BH-CCK-8S，IC50为37.7 μM。
备注	Rebamipide is a cholecystokinin type 1 (CCK1) receptor inhibitor for inhibiting [125I]BH-CCK-8S with IC50 of 37.7 μM.
生化机理	Rebamipide enhances mucosal resistance, increases prostaglandin in gastric mucosa, and also scavenges oxygen-derived free radicals and inhibits their production.
别名	瑞巴派特; 瑞巴匹特; 瑞巴米特; 2-(4-氯苯甲酰胺基)-3-(1,2-二氢-2-氧代-4-喹啉基)丙酸;Mucosta; OPC12759; Proamipide; Rebagen;2-(4-Chlorobenzoylamino)-3-(1,2-dihydro-2-oxo-4-quinolyl)propionic acid