| 应用 |
非选择性毒蕈碱型乙酰胆碱受体激动剂；用于建立癫痫的实验模型。 |
| 产品介绍 |
Pilocarpine盐酸盐是非选择性毒蕈碱乙酰胆碱受体（mAChR）激动剂。 |
| 备注 |
Pilocarpine HCl is a nonselective muscarinic acetylcholine receptor agonist used to produce an experimental model of epilepsy. |
| 生化机理 |
Pilocarpine is a parasympathomimetic alkaloid obtained from the leaves of tropical American shrubs from the genus Pilocarpus. It is a non-selective muscarinic receptor agonist in the parasympathetic nervous system, which acts therapeutically at themuscarinic acetylcholine receptor M3 due to its topical application, e.g., in glaucoma and xerostomia. Pilocarpine acts on a subtype of muscarinic receptor (M3) found on the iris sphincter muscle, causing the muscle to contract and engage in miosis |
| 别名 |
匹鲁卡品 盐酸盐;(3S,4R)-4,5-二氢-3-乙基-4-(1-甲基-1H-咪唑-5-基甲基)-2(3H)-呋喃酮 盐酸盐;(+)-毛果芸香碱盐酸盐;Sanpilo; Salagen; Isopto Carpine; NSC5746; (3S,4R)-4,5-Dihydro-3-ethyl-4-(1-methyl-1H-imidazol-5-ylmethyl)-2(3H)-furanone hydrochloride;(+)-Pilocarpine hydrochloride;Pilocarpine hydrochloride |
