货号 | CAS号 |
---|---|
N125648-50mg | 131060-14-5 |
N125648-5mg | 131060-14-5 |
N125648-10mg | 131060-14-5 |
溶解性 | DMSO |
存贮条件 | 储存温度-20°C |
生化机理 |
NB-598 is a potent competitive inhibitor of squalene epoxidase (SE). NB-598 suppresses triglyceride biosynthesis through the farnesol pathway. SE inhibitor NB-598 significantly inhibited both basal and glucose-stimulated insulin secretion from mouse pancreatic islets. CaV channels were markedly inhibited by NB-598. |