Meclizine 2HCl
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Meclizine 2HCl

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上海阿拉丁生化科技股份有限公司
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产品特点
规格信息
货号 CAS号
M129292-25g 1104-22-9
M129292-5g 1104-22-9
M129292-1g 1104-22-9
M129292-250mg 1104-22-9
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产品描述
  • 分子式 C25H27Cl2N2·2HCl
  • 分子量463.87
  • MDL号 MFCD00058199

属性

熔点 210-213°C
溶解性 Soluble in Chloroform and DMSO
存贮条件 储存温度 2-8°C

描述

应用 A histamine H1 receptor antagonist and pregnane X receptor (PXR) agonist
产品介绍 Meclizine 2HCl 是histamine H1 receptor拮抗剂,用于治疗恶心,晕动病,也是mCAR(组成型雄烷受体激动剂配体)激动剂配体,也是hCAR的反向激动剂。
备注 Meclizine is a histamine H1 receptor antagonist used to treat nausea and motion sickness, has anti-histamine, anti-muscarinic and anti-oxidative phosphorylation properties, also an agonist ligand for mCAR (constitutive androstane receptor) and an i
生化机理 Meclizine Dihydrochloride is a pregnane X receptor (PXR) agonist and histamine H1 receptor antagonist. The compound also possesses anticholinergic, central nervous system depressant, and local anesthetic effects. Meclizine depresses labyrinth excitability and vestibular stimulation and may affect the medullary chemoreceptor
别名 盐酸美克洛嗪; 盐酸氯苯苄嗪; 1-((4-氯苯基)苯甲基)-4-((3-甲苯基)甲基)哌嗪二盐酸盐;1-(p-Chloro-α-phenylbenzyl)-4-(m-methylbenzyl)-piperazine dihydrochloride ;1-[(4-Chlorophenyl)phenylmethyl]4-[(3-methylphenyl)methyl]piperazine dihydrochloride ;NSC 28728;Meclozine dihydrochloride; Bonamine; Postafen; Parachloramine
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