货号 | CAS号 |
---|---|
M127999-5mg | 103909-75-7 |
M127999-1mg | 103909-75-7 |
M127999-50mg | 103909-75-7 |
M127999-10mg | 103909-75-7 |
溶解性 | DMSO |
存贮条件 | 储存温度-20°C |
生化机理 |
Maxacalcitol?(22-Oxacalcitriol) is non-calcemic vitamin D3 analog and VDR ligand. Maxacalcitol(22-Oxacalcitriol)?is VDR-like Receptors. Maxacalcitol (22-Oxacalcitriol)suppresses parathyroid hormone (PTH) mRNA expression in vitro and in vivo. Maxacalcitol exhibits similar effects to calcitriol in osteoblast-like cells. Maxacalcitol(22-Oxacalcitriol) inhibits tumor growth of osteosarcoma in vitro in combination with all-trans retinoic acid. |