货号 | CAS号 |
---|---|
A127302-50mg | 1206880-66-1 |
A127302-5mg | 1206880-66-1 |
A127302-10mg | 1206880-66-1 |
溶解性 | DMSO |
存贮条件 | 储存温度-20°C |
生化机理 |
AM679 is a drug which acts as a selective inhibitor of 5-Lipoxygenase-activating protein (FLAP). This protein is involved in the production of cysteinyl leukotrienes which are involved in inflammation, and AM679 has anti-inflammatory effects in animal studies. AM679 also showed potent inhibition of leukotrienes in human blood and in a rodent bronchoalvelolar lavage (BAL) challenge model. Research showed AM679 reduces inflammation in the respiratory syncytial virus-infected mouse eye. |