Linagliptin

属性

溶解性	Soluble in DMSO (17 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), ethanol (1 mg/ml at 25 °C), 0.5% hyroxyethylcellulose (30 mg/ml at 25 °C), and methanol.
存贮条件	储存温度-20°C

描述

应用	A highly potent, selective CD26 (DPP-4) inhibitor.
产品介绍	Linagliptin是一种高效的，选择性的DPP-4抑制剂，IC50为1 nM。
备注	Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM.
生化机理	inagliptin is a highly potent, selective CD26 (DPP-4) inhibitor with IC50 of 1 nM.
别名	BI 1356;利拉利汀; 8-[(3R)-3-氨基-1-哌啶基]-7-(2-丁炔基)-3,7-二氢-3-甲基-1-[(4-甲基-2-喹唑啉基)甲基]-1H-嘌呤-2,6-二酮;BI 1356;Tradjenta;BI1356;BI-1356; (R)-8-(3-aminopiperidin-1-yl)-7-(but-2-ynyl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione;8-[(3R)-3-Amino-1-piperidinyl]-7-(2-butynyl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione