AZD3463

属性

溶解性	25°C: DMSO
存贮条件	储存温度-20°C

描述

产品介绍	AZD-3463是ALK/IGF1R抑制剂。
备注	AZD3463 is a novel orally bioavailable ALK inhibitor with Ki of 0.75 nM, which also inhibits IGF1R with equivalent potency.
生化机理	AZD-3463 is an ALK/IGF1R inhibitor which overcomes multiple mechanisms of acquired resistance to crizotinib.
别名	ZD3463;AZD 3463; N-(4-(4-氨基-1-哌啶基)-2-甲氧基苯基)-5-氯-4-(1H-吲哚-3-基)-2-嘧啶胺;;AZD3463;AZD 3463;ALK/IGF1R inhibitor;N-(4-(4-amino-1-piperidinyl)-2-methoxyphenyl)-5-chloro-4-(1h-indol-3-yl)-2-pyrimidinamine;