BMS-536924

属性

溶解性	DMSO 96 mg/mL Water <1 mg/mL Ethanol <1 mg/mL
存贮条件	储存温度-20°C

描述

备注	BMS-536924 is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity for Akt1, MAPK1/2.
生化机理	BMS-536924 is a small molecule ATP-competitive IGF-IR kinase inhibitor with with an IC50 of 80 nM.