Vandetanib (ZD6474)

属性

溶解性	Soluble in methanol, DMSO (4 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), and ethanol (<1 mg/ml at 25 °C).
存贮条件	储存温度-20°C

描述

应用	An antagonist of VEGFR (Flk and Flk) and EGFR families.
产品介绍	Vandetanib is an antagonist of VEGFR (Flk and Flk) and EGFR families. Specifically inhibits kinase activity of Flk-1. Vandetanib is an inhibitor of Flt-4.
备注	Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 with IC50 of 40 nM.Phase 1/2
别名	凡德他尼;ZD6474;N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine