货号 | CAS号 |
---|---|
M127968-5mg | 1001917-37-8 |
溶解性 | DMSO |
存贮条件 | 储存温度-20°C |
生化机理 |
MK-8033 is a c-MET inhibitor in clinical trials. MK8033 is a selective small-molecule inhibitor, ATP competitive. Phase I investigation of the cMet inhibitor MK-8033 is ongoing. Plans include a trial of this agent in refractory colorectal cancer, with pre- and post-treatment biopsies to evaluate for relevant molecular signatures. |