| 货号 | CAS号 |
|---|---|
| P107388-25mg | 81131-70-6 |
| P107388-500mg | 81131-70-6 |
| P107388-100mg | 81131-70-6 |
| 熔点 | 171°C-173°C |
| 敏感性 | 对热敏感 |
| 溶解性 | Soluble in water |
| 存贮条件 | 储存温度 2-8°C |
| 应用 | An HMGCR inhibitor which blocks cholesterol synthesis. |
| 产品介绍 | Pravastatin sodium是一种HMG-CoA还原酶抑制剂，能抑制甾醇合成，其IC50为5.6 μM。 |
| 生化机理 | Pravastatin, Sodium Salt is a competitive HMGCR (HMG-CoA reductase) inhibitor that potently blocks cholesterol synthesis (Ki ~1 nM). Pravastatin offers cardioprotection and also acts as an immunomodulator and as an inhibitor of ras p21 isoprenylation. |
| 别名 | 普伐他汀钠;1,2,6,7,8,8a-六氢-2-甲基-8-(2-甲基丁酰氧基)-1-萘-3',5',6-三羟基庚酸钠盐;(βR,δR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β,,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid monosodium salt; Pravastatin sodium salt;[1S-[1a(bS,dS),2a,6b,8b(R),8aa]]-1,2,6,7,8,8a-Hexahydro-b,d,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphthaleneheptanoic acid monosodium salt;Eptastatin sodium |
