1-palmitoyl-2-(5'-oxo-valeroyl)-sn-glycero-3-phosphocholine
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1-palmitoyl-2-(5'-oxo-valeroyl)-sn-glycero-3-phosphocholine

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上海阿拉丁生化科技股份有限公司
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产品特点
规格信息
货号 CAS号
P130753-1mg 121324-31-0
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产品描述
  • 分子式 C29H56NO9P
  • 分子量593.73
  • Beilstein号
  • EC号
  • MDL号
  • PubChem编号

属性

存贮条件 储存温度 -20°C

描述

应用 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine (POVPC) has been used:
· to study its effects on endothelial function and vasodilation
· as a ligand for LRP6 in bone marrow mesenchymal stromal cells (MSCs)
· as a oxidized lipid to study if membrane status at different degrees of lipid peroxidation is involved in oxidative stress toleranc
产品介绍 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine (POVPC) is a derivative of oxidized Low density lipoprotein (oxLDL), a proinflammatory lipid present in atherosclerotic lesions
生化机理 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine (POVPC) affects endothelial function by hindering activity of endothelial nitric oxide synthase and stimulating endothelial cell apoptosis. It is implicated in the development of atherosclerosis and it may be used as a potent therapeutic for atherosclerosis
别名 POVPC;POVPC; 1-palmitoyl-2-(5′-oxo-valeroyl)-sn-glycero-3-phosphocholine, powder
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